In a shallow bowl stir together milk and hot sauce.
In another shallow bowl combine cornmeal, salt, pepper, paprika, and cayenne.
Dip the fish in the milk, then dredge in the cornmeal mixture, coating thoroughly.
Let sit for a few minutes while you heat about 2 inches of oil to 350 degrees in a deep cast-iron pot (a thermometer is immensely helpful in maintaining the oil temperature; adjust your heat accordingly).
When oil is hot, gently add the fish (a few pieces at a time—don’t crowd the pot) and fry until golden brown, about 3 or 4 minutes.
Let drain on paper towels and serve with lemon wedges or your preferred sauce.